St. Anne (sometimes spelled Saint Anne) is a village in Kankakee County, Illinois, United States. The population was 1,161 at the 2020 census. It is allocation of the Kankakee–Bourbonnais–Bradley Metropolitan Statistical Area. It was founded in 1851 by Charles Chiniquy, a French-Canadian Roman Catholic priest and buddy of the 16th U.S. President Abraham Lincoln who was excommunicated by the Roman Catholic Church in 1856. He well along converted to Protestant Christianity, becoming a Presbyterian Evangelical minister and a well-known temperance campaigner in Canada and the United States.

St. Anne is located in southeastern Kankakee County at 41°1′24″N 87°43′1″W / 41.02333°N 87.71694°W / 41.02333; -87.71694 (41.023363, -87.717050). Illinois Route 1 passes through the west side of the village. It is 13 miles (21 km) southeast of Kankakee, the county seat, and 18 miles (29 km) north of Watseka.

According to the 2010 census, St. Anne has a total Place of 0.793 square miles (2.05 km), of which 0.77 square miles (1.99 km²) (or 97.1%) is estate and 0.023 square miles (0.06 km) (or 2.9%) is water.

As of the census of 2000, there were 1,212 people, 464 households, and 330 families residing in the village. The population density was 2,385.3 inhabitants per square mile (921.0/km²). There were 486 housing units at an average density of 956.5 per square mile (369.3/km). The racial makeup of the village was 89.85% White, 0.83% African American, 0.41% Native American, 0.08% Asian, 0.08% Pacific Islander, 6.60% from supplementary races, and 2.15% from two or more races. Hispanic or Latino of any race were 10.48% of the population.