Medford is a city in Taylor County, in north-central Wisconsin, United States. The population was 4,349 at the 2020 census. The city is located mostly within the boundaries of the Town of Medford. It is the county chair of Taylor County.

Medford is located upon historic Ojibwe forest house acquired by the United States in the 1837 Treaty of St. Peters. In 1864, the federal government authorized a ascend of some 837,000 acres (1,308 sq mi; 3,390 km) of this house to subsidize railway construction through the area. The Wisconsin Central Railroad Company, controlled by Boston financier Gardner Colby, obtained the land allow and build up the railroad in the 1870s. The railroad company and a local lumber milling company laid out the city of Medford in 1875 and sold lots for twenty-five dollars each. The railroad named the new agreement after Medford, Massachusetts, the hometown of a railroad official. Medford shipped beyond 1.5 million board feet of lumber by rail within a year of its establishment, and the area was soon determined cut for farming.

The Wisconsin Legislature organized Taylor County in 1875 and named Medford the county seat, leading to a argument between the Wisconsin Central Railroad and the mill company higher than the location of the courthouse. The Taylor County Courthouse was ultimately build up on house donated by the railroad company.

In the 1960s and 1970s, Medford hosted an annual Mink festival, celebrating the town’s affirmation to be the “Mink capital of the world.” Fur farms in the Place make Taylor County a top mink producer in North America. During the COVID-19 pandemic, in 2020, thousands of mink died of the virus after having established it from human workers.