Saulsbury is a town in rural Hardeman County, Tennessee. It is located along State Highway 57 in southwest Hardeman County. The population was 99 at the 2000 census and 81 at the 2010 census showing a decline of 18. Saulsbury is the least-populated incorporated municipality in Tennessee.

Saulsbury’s historical roots stem from a former unity named Berlin, Tennessee, which was located one mile south of the current location of Saulsbury. Two regional mail roads—one from Bolivar to Ripley, Mississippi, and different from LaGrange to Corinth, Mississippi. These mail roads met at an intersection which would form into a trading center. In 1839 a name office was standard there, and Berlin would be incorporated in 1846, and within five years it would be home to 351 people. Upon the finishing of the Memphis and Charleston Railroad, Berlin was bypassed due to one landowner’s refusal to sell their property to the railroad. A track was instead laid one mile north of Berlin, on house that was owned by Burrell Sauls and Berry Futrell. The ended railroad station and track would be called Sauls-Berry Depot. Eventually Berlin would be unaccompanied as people moved to the new harmony and in 1856 Saulsbury was incorporated.

Just after the taking of Memphis in 1862, the Union Army took Saulsbury. Skirmishes continued throughout the area, and eventually Saulsbury would compensation to Confederate control. Confederate soldiers used Saulsbury as a rally reduction to travel to Corinth to associate their regiments. After the Civil War, Saulsbury maintained itself as a town, unlike others in the area which barely survived the war. Saulsbury’s cotton production survived the feat as well, and Saulsbury emerged as a leader in cotton production in the region. The town after that became a producer of eggs, turkeys, poultry and hogs; which were often sent to Memphis for sale. Sand mining became a major industry in the 1870s, providing 47 alternating types of sand for brass molding.

On January 17, 1999, an F1 tornado formed just southwest of Saulsbury, and moved northeast until dissipating near Rogers Springs. One person was killed, four others were injured. Fourteen houses and mobile homes were destroyed, and twenty-seven others were damaged. Power lines and trees also sustained significant damage.^{[citation needed]}
As a result, the town of Saulsbury installed a tornado fright at the local blaze station, the solitary one in the area at the time.