Lexington is a city in Henderson County, Tennessee, United States. Lexington is midway in the midst of Memphis and Nashville, lying 10 miles (16 km) south of Interstate 40, which connects the two cities. The population was 7,956 at the 2020 census. It is the county seat of Henderson County.

Shortly after the 1821 launch of Henderson County, a site close its middle was selected as a county seat, and was named in great compliment of Lexington, Massachusetts, site of the first fight of the American Revolution. Land Grant holder Samuel Wilson gave the estate for the town, retaining a lot upon the square where his home was already situated. The square is oriented suitably the corners tapering off to the cardinal points on the compass.^{[citation needed]} The first county courthouse was built in 1823; Lexington was incorporated in 1824 and by 1830 had a population of 260.

As the lead-up to the Civil War began, Henderson County voted neighboring secession. As the encounter progressed, both Union and Confederate regiments were recruited in the county. The area in and something like Lexington was the site of a skirmish on December 18, 1862. Union Colonel Robert Ingersoll sent his troops to destroy a bridge on summit of Beech Creek to disallow the Confederate army moving into the area. However, Ingersoll’s troops did not destroy the bridge, and General Nathan Bedford Forrest’s troops headed into Lexington. Forrest’s troops overtook the Union soldiers, taking beyond 140 men, including Colonel Ingersoll, and collected artillery and supplies left in back by Union soldiers who escaped.

In 1918, an African-American man called Berry Noyse who was accused of killing the sheriff was lynched by a mob in the courthouse square and burned in the street.