Macon is a city in and the county seat of Macon County, Missouri, United States. The population was 5,457 at the 2020 census.

Macon was platted in 1856. Like the county, Macon was named for Nathaniel Macon. A pronounce office called Macon City was standard in 1856, and the declare was distorted to Macon in 1892.

In May 1898, there was a string of break-ins in the area of Macon. The break-ins included the theft of food and items, as with ease as assaults upon women. In late June, there was a break-in at the home of John Koechel, a blind broom maker. During this break-in, there were references to previous assaults, an attempted assault, and a theft of two sacks of flour. Police officers followed a trail of tiny white specks to the house of Henry Williams, who was well ahead arrested similar to no resistance. The night of Williams’ arrest, crowds formed at the courthouse, while a local pastor, Rev. G. A. Robbins, plead for the crowd to permit the put on an act to take its proper course. The crowd moved upon to the jail, and demanded Sheriff A. J. Glenn give up Williams, Glenn and his deputies refused the crowd’s demands. A man called Mr. McVicker made a speech to attempt to pacify the crowd, but was numb by a thrown brick. The crowd knocked by the side of the fence, stole the key, and unlocked Williams’ cell, confronting the cowering man. The mob of 200-300 men contracted they would hang him from a bridge instead of electrical lights, so they would not upset the women and kids in the morning. In the early hours of daylight hours of June 30, 1898, Henry Williams was lynched upon the Wabash bridge, he maintained his innocence bearing in mind asked if he wanted to say anything.

In November 1919 four African-Americans were arrested for allegedly robbing a white farmer. They were held at the Macon prison but on Saturday, November 15, 1919, a white mob drove into town and demanded that the Sheriff hand them over. At first he refused but considering the mob threatened to use dynamite to ruin the prison the four black men were handed beyond and they were next driven to Moberly, Missouri and lynched.