Francisville is a census-designated place (CDP) in Boone County, Kentucky, United States. Its population was 7,944 as of the 2010 census. Francisville shares ZIP code 41048 subsequent to the adjoining CDP of Hebron. It is the northernmost community in the state.

Francisville was founded in 1819, when 77 members of the Bullitsburg Baptist Church granted to verify a church closer to their homes. The Sand Run Baptist Church was built for a cost of $2100. A state office, general store, school, hotel, and tobacco warehouse soon developed nearly the church.

Francisville is served by one daily newspaper, The Kentucky Enquirer (an edition of The Cincinnati Enquirer), and by one weekly newspaper, The Boone County Recorder. Francisville is furthermore served by twelve television stations and many radio stations as allocation of the Greater Cincinnati media market.

Francisville is located in northern Boone County, on the southwestern side of the Cincinnati Metropolitan Area. Interstate 275, the beltway going on for Cincinnati, forms the southern edge of the CDP, with the community of Hebron to the south of I-275. Francisville extends to the north as far-off as Kentucky Route 8 (River Road) in the Ohio River valley. Kentucky Route 237 (North Bend Road) is the main road through Francisville, extending from KY 8 south to I-275 and more than into Hebron and Burlington. The contact to Cincinnati/Northern Kentucky International Airport is located 4 miles (6 km) southeast of Francisville.