Semmes (pronounced , locally /sɪmz/) is a city in western Mobile County, Alabama, in the Mobile metropolitan area. It was incorporated in 2011. As of the 2020 census, the population was 4,941.

The community was named for Admiral Raphael Semmes (1809–1877), an superintendent in the United States Navy from 1826 to 1860 and the Confederate States Navy from 1860 to 1865.

On March 3, 2010, the members of the Friends of Semmes and the joined Incorporate Semmes organizations presented Mobile County Probate Judge Don Davis considering a petition seeking to incorporate an Place within the Semmes community as the City of Semmes. The proposed combination did not enlarge the entire area known as Semmes due to distinct population density requirements of Alabama acknowledge law. Judge Davis set the date for the referendum as Tuesday, August 17, 2010. After voting closed, unofficial returns showed the plebiscite passing with 74.19% of the voters well-disposed of incorporation. Some voters complained not quite the “zig-zag” nature of the proposed city limits, which excluded some areas of the community from the vote, with some referring to the proposed city as a gerrymander.

Once the election was attributed in August, the Mobile County Probate Judge ordered an enumeration, or census, of the citizens of the extra municipality, in accordance following Alabama law. The enumeration was completed in late April 2011, and the city was avowed incorporated by the Probate Judge on May 2, 2011. The Probate Judge set the date of the first municipal election to be June 28, 2011, to elect the mayor and the five at-large city council seats. The city of Mobile, upon the issuance of the order of incorporation, removed Semmes from its police, fire, and planning extraterritorial jurisdictions, and no longer provides any services or collects any taxes in the area.