Kewaunee is a city in Kewaunee County, Wisconsin, United States. The population was 2,837 at the 2020 census. Located on the northwestern shore of Lake Michigan, the city is the county chair of Kewaunee County. Its Menominee name is Kewāneh, an outdated name for a species of duck.

Kewaunee is allocation of the Green Bay Metropolitan Statistical Area.

Kewaunee was the site of a Potawatomi village at the times of European right of entry in the seventeenth century. French Jesuit missionary Jacques Marquette applauded All Saints Day at the Potawatomi village in 1674.^{: 371–372} Later, French buccaneer René-Robert Cavelier, Sieur de La Salle visited the village in 1679,^: 215 and Canadian Jesuit Jean-François Buisson de Saint-Cosme stopped in September 1698.^: 262 The Potawatomis moved south and east along Lake Michigan in the eighteenth century, and the Place was reclaimed by Menominee people. Trader Jacques Vieau received a short lived trading name for the North West Company in the Place of Kewaunee in 1795. The United States acquired the home from the Menominee nation in the 1831 Treaty of Washington.

The current concurrence at Kewaunee began in 1836, when false rumors of gold deposits in the Kewaunee River triggered a teenage gold hurry of Yankee settlers. Land explorer Joshua Hathaway surveyed and platted the settlement. When no gold was found, the settlers who remained time-honored a sawmill and developed the local harbor for the lumber industry.^{: 427–428} Kewaunee became the county seat of Kewaunee County at the become old of the county’s formation in 1852. In the late nineteenth century, the community attracted many Czech and German immigrants.