Fort Chiswell is a census-designated place (CDP) in Wythe County, Virginia, United States. The population was 939 at the 2010 census.

Fort Chiswell is located at the junction of Interstates 77 and 81. Going west from Fort Chiswell, drivers find themselves upon a double wrong-way concurrency – one of few in the nation. Interstate 77 northbound is overlapped with Interstate 81 southbound, drivers will find themselves oriented the right pretentiousness again taking into account exiting I-81 encourage to I-77 north towards Charleston or south to Charlotte.

The community reveal is derived from a frontier fort built in 1758 as an outpost during the French and Indian War. The fort, which was of strategic importance during the American Revolution as the guardpost beyond a little deposit of benefit used to mold bullets, was situated at the junction of the Great Trading Path and the Richmond Road, near the New River. The fort fell into disrepair in the 18th century as both the county chair and courthouse were moved from Fort Chiswell to the county seat of Wytheville, 12 miles to the west. The remaining foundations of the Fort and its surrounding buildings were utterly covered more than during the construction of I-77 in Wythe County during the 1970s. There is a pyramid shaped historical marker of sandstone situated approximately 200 yards west-northwest of the fort’s indigenous location next to the out of date chicken house.

The Fort Chiswell Site, The Mansion at Fort Chiswell, and McGavock Family Cemetery are listed on the National Register of Historic Places.