Scipio is a town upon the eastern edge of Millard County, Utah, United States. The population was 290 at the 2000 census.

According to the United States Census Bureau, the town has a total Place of 5.5 square miles (14 km), all land. It lies in the oval-shaped Round Valley, 37 miles (60 km) south-southwest of Nephi, at the junction of Interstate 15 (I‑15) and U.S. Route 50 (US‑50). The nearest town, approximately 15 miles (24 km) southwest upon I‑15, is Holden. About 30 miles (48 km) south-southeast are the towns of Redmond, Salina, and Aurora. About halfway in the company of Scipio and Salina is Lake Scipio, on the west side of US‑50. To the east lie the Valley Mountains, with the highest top reaching vis-а-vis 8,189 feet (2,496 m). To the south are the Pahvant Mountains, which rise above 10,000 feet (3,000 m).

According to the Köppen Climate Classification system, Scipio has a hot-summer humid continental climate, abbreviated “Dfa” on climate maps. The hottest temperature recorded in Scipio was 107 °F (41.7 °C) on July 18, 1998, while the coldest temperature recorded was −40 °F (−40.0 °C) on January 9, 1937 and January 22, 1937.

As of the census of 2000, there were 290 people, 112 households, and 91 families residing in the town. The population density was 340.8 people per square mile (131.7/km²). There were 139 housing units at an average density of 163.4 per square mile (63.1/km). The racial makeup of the town was 97.59% White, 0.34% Native American, 0.69% from extra races, and 1.38% from two or more races. Hispanic or Latino of any race were 3.79% of the population.