San Elizario is a city in El Paso County, Texas, United States. Its population was 13,603 at the 2010 census. It is share of the El Paso metropolitan statistical area. It lies upon the Rio Grande, which forms the be next-door to between the United States and Mexico. The city of Socorro adjoins it on the west and the town of Clint lies to the north.

In 1598, Don Juan de Oñate, a Spanish nobleman and conquistador born in Zacatecas, Mexico, led a help of 539 colonists and 7,000 head of livestock (including horses, oxen, and cattle) from southern Chihuahua to have the same opinion the province of New Mexico. The caravan traveled a northeasterly route for weeks across the desert until it reached the banks of the Rio Grande in the San Elizario area. A addition was held, a blessing of the gratifying and a celebration. Oñate performed the ceremony of La Toma (“Taking Possession”), in which he claimed the new province for King Philip II of Spain. This is considered to be the “Birth of the American Southwest”.

The unity that became
San Elizario was first acknowledged sometime in the past 1760 as the civilian treaty of Hacienda de los Tiburcios. The hacienda was located along the route of Camino Real de Tierra Adentro southeast of Socorro on the west bank of the Rio Grande. The hacienda was eventually unaccompanied by the 1770s.^: 46–47

In 1789, the site of the archaic hacienda Tiburcios became the supplementary site where the Spaniards relocated a fort called Presidio de San Elzeario. It had originally been standard in 1774, located farther south in the El Paso Valley near the site of avant-garde El Porvenir. It had been moved north to be better competent to protect the Camino Real and the towns of to its north, Socorro and Ysleta.^: 46