Navasota is a city in Grimes County, Texas, United States. The population was 7,643 at the 2020 census. In 2005, the Texas Legislature designated Navasota as the “Blues Capital of Texas” in award of the late Mance Lipscomb, a Navasota indigenous and blues musician.

Navasota is located in southwestern Grimes County, Texas, east of the Navasota River (a tributary of the Brazos River). It is 71 miles (114 km) northwest of Houston. Texas State Highway 105 is the main east–west route that passes through the center of Navasota, leading southwest 25 miles (40 km) to Brenham and east 41 miles (66 km) to Conroe. Texas State Highway 6 passes north–south through the eastern side of the city as a four-lane bypass, leading northwest 22 miles (35 km) to College Station and south 21 miles (34 km) to Hempstead.

According to the United States Census Bureau, the city has a total area of 7.4 square miles (19.1 km), of which 0.04 square miles (0.1 km²), or 0.47%, is water.

French buccaneer René-Robert Cavelier, Sieur de La Salle, misguided in his 1687 attempt to find the Mississippi River and maddening to locate his way put going on to to French-held lands near the Great Lakes, came through the Place which would become Navasota. It was there that La Salle was murdered by one of his men. After numerous voyages, explorations of the Mississippi River valley, trading ventures and several mutinies, La Salle’s bones are believed to have found their resting place in the Navasota Valley.