Mobeetie is a city in northwestern Wheeler County, Texas, United States, located upon Sweetwater Creek and State Highway 152. Its population was 101 at the 2010 census, six under the 2000 figure.

Mobeetie (formerly known as “Cantonment Sweetwater”) was a trading herald for hunters and trappers for welcoming United States Army outpost Fort Elliott. It was first a buffalo hunters’ camp unofficially called “Hidetown”. Connected to the major cattle-drive town of Dodge City, Kansas, by the Jones-Plummer Trail, Mobeetie was a destination for stagecoach freight and buffalo skinners. As it grew, the town supported the improvement of cattle ranches within a hundred-mile radius by supplying the staple crops.

The first formal herald for the town was “Sweetwater”. It was located on the North Fork Red River, a tributary of the Red River of the South. Nearby Fort Elliott, developed to guard the buffalo trade from Indian raiders, stimulated further buildup of the town. On January 24, 1876, the “Sweetwater Shootout” occurred. Anthony Cook (Corporal “Sergeant” Melvin A. King; of the then-4th Cavalry Company H, stationed at Fort Elliot) shot and killed Mollie Brennan (a dancehall woman and former prostitute). Sgt. King after that wounded Bat Masterson, who in outlook killed him (King may have shot Masterson first and subsequently killed Brennan; accounts vary). Texas cattleman Charles Goodnight said just about the town: “I think it was the hardest place I ever saw on the frontier except Cheyenne, Wyoming.”

When the town applied for a make known office in 1879, the name “Sweetwater” was already in use. The town took the additional name of “Mobeetie”, believed to be a Native American word for Sweetwater. It was allegedly higher revealed that the word, in fact, meant “buffalo dung.”