Henrietta is a city in and the county seat of Clay County, Texas, United States. It is portion of the Wichita Falls metropolitan statistical area. The population was 3,141 at the 2010 census, a subside of 123 from the 2000 tabulation of 3,264.

Henrietta is one of the oldest granted towns in north central Texas. It sits at the crossroads of U.S. Highway 287, U.S. Highway 82, State Highway 148, and Farm to Market Road 1197 in north central Clay County.

Clay and Montague counties were not speaking in 1857 from Cooke County to the east, and Henrietta was named as the county seat. The naming of the town remains a mystery, though several explanations have been offered. Regardless of the line of its name, Henrietta became the center of gravity for the fledgling county. In 1860, as the on your own town in the county, it had 109 residents, 10 houses, and a general store. It sat at the far away western edge of Anglo move ahead in north-central Texas, but Native Americans remained a possible threat to current and highly developed settlers. In 1862, Henrietta opened its read out office. In the to the front 1860s, there were continuous attacks from local tribes. By late 1862, Henrietta was abandoned, and white settlers returned east to Cooke and Montague counties. Remaining structures were burned. Anglos continued to try resettlement, and in 1865 after the Civil War, a bureau attempting resettlement was massacred. A number of Quakers attempted to reoccupy the former townsite, but its members were either killed or fled. In 1870, fifty soldiers and Kiowa Indians fought a fight in the ruins of Henrietta.

After the battle, white settlers returned to Henrietta, this era permanently. In 1874, the broadcast office reopened, and Henrietta quickly became the economic hub of north-central Texas. In 1882, the Fort Worth and Denver Railway reached Henrietta on its southern side, and in 1887, Henrietta became the westernmost terminus for the Gainesville, Henrietta, and Western Railway.