Pikeville is a city in Bledsoe County, Tennessee, United States. The population was 2,251 at the 2010 census. It is as well as the county seat of Bledsoe County.

The Sequatchie River valley was ration of Cherokee lands until 1805, when the Cherokee ceded it to the U.S. as allocation of the Treaty of Tellico. By the late 18th century, the valley had been identified by hunters, one of whom, Anthony Bledsoe (1739-1788), became the county’s namesake. Bledsoe County was formed in 1807, with the town of Madison as its county seat.

Pikeville was normal in 1816 on lands donated by Charles Love, an to the lead Sequatchie settler. The origin of the town’s reveal is unknown, although some have suggested that it was named for buccaneer General Zebulon Pike. By 1818, the Bledsoe County chair had been moved from Madison to Pikeville. The town was incorporated in 1830.

J.V. Wigle (1890–1970), a combustion engineer from Michigan and laboratory partner in crime at Eastern Michigan University, met a local woman, Mattie Lawson, and contracted down in Pikeville. He first brought electricity to town afterward he electrified the home where he lived close the corner of Poplar and Wiegle streets (Wiegle Street, named after J.V. Wigle, is misspelled). In adjunct to bringing electricity to Pikeville, Wigle bottled Coca-Cola and made wrought iron railings in the community. He was decided two U.S. patents in 1931 (1,798,289 & 1,814,535) for a coin selecting device and a braking mechanism. His two sons attended the engineering hypothetical at Vanderbilt University. His son Tom (1933–2006) helped build U.S. Route 127 heading north out of town as it rises going on the mountain close the county line, during a summer job together with semesters at Vanderbilt. Wigle is buried behind his wife in Pikeville City Cemetery in the relatives plot, along like Tom Wigle.