Huntingdon is a borough in (and the county chair of) Huntingdon County, Pennsylvania, United States. It is located along the Juniata River, approximately 32 miles (51 km) east of Altoona and 92 miles (148 km) west of Harrisburg. With a population of 7,093 at the 2010 census, it is the largest population center near Raystown Lake, a winding, 28-mile-long (45 km) flood-control reservoir managed by the U.S. Army Corps of Engineers.

The borough is located upon the main heritage of the Norfolk Southern (formerly Pennsylvania) Railway, in an agricultural and external recreational region considering extensive forests and scattered deposits of ganister rock, coal, fire clay, and limestone. Historically, the region surrounding Huntingdon was dotted with iron furnaces and forges, consuming limestone, iron ore and wood (for charcoal production) throughout the 19th century. Dairy farms dominate the local agriculture. The town is a regular End for the Amtrak passenger advance which connects Harrisburg like Pittsburgh.

Huntingdon is home to Juniata College, a private unprejudiced arts university founded by members of the Church of the Brethren in 1876.

The indigenous inhabitants of Huntingdon and against counties were the Susquehannock. Through a incorporation of ongoing prosecution with other native nations, such as the Haudenosaunee, disease brought by Europeans, and exploit from settlers, the Susquehannock are currently thought to have been unconditionally wiped out or subsumed by new tribes.