Hopwood is a census-designated place (CDP) in Fayette County, Pennsylvania, United States. The population was 2,090 at the 2010 census, up from 2,006 at the 2000 census. It is located in North Union and South Union townships. The village was named after John Hopwood.

Hopwood is located in central Fayette County at 39°52′27″N 79°42′12″W / 39.87417°N 79.70333°W / 39.87417; -79.70333 (39.874145, -79.703385). It is bordered to the north by East Uniontown. U.S. Route 40 Business (National Pike) runs through the center of Hopwood and forms the be adjacent to between North and South Union townships. The middle of Uniontown is 2 miles (3 km) to the northwest via National Pike. U.S. Route 40 forms a four-lane bypass on the south side of Uniontown, intersecting National Pike at the south grow less of Hopwood. Via US 40 it is 60 miles (97 km) southeast to Cumberland, Maryland, and 45 miles (72 km) northwest to Washington, Pennsylvania.

According to the United States Census Bureau, the Hopwood CDP has a total area of 1.89 square miles (4.89 km), all of it land. The community sits at the western base of Chestnut Ridge, the westernmost ridge of the Allegheny Mountains in this area.

As of the census of 2000, there were 2,006 people, 893 households, and 584 families residing in the CDP. The population density was 1,070.8 people per square mile (414.2/km²). There were 932 housing units at an average density of 497.5/sq mi (192.4/km). The racial makeup of the CDP was 98.60% White, 0.60% African American, 0.10% Native American, 0.25% Asian, 0.05% Pacific Islander, 0.10% from extra races, and 0.30% from two or more races. Hispanic or Latino of any race were 0.25% of the population.