Jackson is a city in and the county chair of Jackson County, Ohio, United States approximately 27 mi (43 km) SE of Chillicothe. The population was 6,239 at the 2020 census.

Established in 1817, residents named the town after Andrew Jackson, a hero of the War of 1812, and an eventual president of the United States. The community grew slowly, having single-handedly 297 inhabitants in 1840. In 1846, Jackson contained four churches, about seven stores, and a single newspaper office. Over the adjacent 40 years, the town grew quickly, attaining a population of 3,021 people in 1880. By 1880, two railroad lines passed through the community, helping to spur economic and population growth. In 1886, two newspaper offices, eight churches, and two banks existed in Jackson. The largest businesses in the town were the Star Furnace Company and the Globe Iron Company, with 30 employees apiece. Both firms used local coal and iron ore deposits to make iron products.

Jackson continued to increase during the 20th century. Jackson was the county’s largest community in 2000, with a population of 6,184 people. This number amounted to regarding 20% of the county’s entire population. Today, many locals find employment in a General Mills forest in manageable Wellston, Ohio, which employs beyond 1000 people.

According to the United States Census Bureau, the city has a total area of 8.49 square miles (21.99 km), of which 8.23 square miles (21.32 km²) is house and 0.26 square miles (0.67 km) is water.