Moncure, founded in 1881, is a little rural unincorporated community in southeastern Chatham County, North Carolina, United States. Moncure and the neighboring community of Haywood form the Moncure census-designated place (CDP), which had a population of 711 at the 2010 census. The community is located close the confluence of the Deep and Haw rivers, which form the Cape Fear River. Moncure subsequently served as the westernmost inland port in the state, linked to the Atlantic Ocean by steamships.

Moncure is located in southeastern Chatham County, at 35.622N latitude and -79.078W longitude, and at an height above sea level of nearly 213 feet (65 m). It is bordered on the south by the Deep River, which forms the boundary with Lee County to the south. The Moncure CDP includes the village of Moncure, plus the smaller community of Haywood to the east; both are located along Old US Highway 1. The CDP extends as far away east as the Haw River and as far-off south as the junction of the Haw gone the Deep River to form the Cape Fear River. U.S. Route 1, a four-lane expressway, passes through Moncure north of the village center, with entry from Exit 79. US 1 leads northeast 28 miles (45 km) to Raleigh, the own up capital, and southwest 12 miles (19 km) to Sanford. The Place forms a salient or panhandle of Chatham County, lying between Wake and Lee Counties.

According to the United States Census Bureau, the Moncure CDP has a total area of 4.9 square miles (12.8 km), of which 4.7 square miles (12.2 km²) is land and 0.23 square miles (0.6 km), or 4.61%, is water.

The B. Everett Jordan Lake Dam is located just north of Moncure, and the Place is house to much of Chatham County’s unventilated industry, including Shearon Harris Nuclear Power Plant 8 miles (13 km) to the east, and several plywood and lumber plants.