Hopewell Junction is a hamlet and census-designated place (CDP) in Dutchess County, New York, United States. The population was 1330 at the 2020 census. It is allowance of the Poughkeepsie–Newburgh–Middletown, NY Metropolitan Statistical Area as skillfully as the larger New York–Newark–Bridgeport, NY-NJ-CT-PA Combined Statistical Area.

Hopewell Junction is located within the town of East Fishkill. It was originally a railroad junction where the Newburgh, Dutchess and Connecticut Railroad met the New York and New England Railroad and Dutchess County Railroad. All three became part of the New York, New Haven and Hartford Railroad system, and the ND&C to the southwest and the NY&NE are now owned by the Housatonic Railroad and used by Metro-North for equipment moves in the midst of its Hudson Line and Harlem Line. The last permanent section of passenger line, a branch from Pine Plains, south through Milbrook, to Hopewell Junction, to Beacon, lost its passenger assist at some tapering off between 1932 and 1938. The closest passenger capacity is Beacon station on Metro-North’s Hudson Line. Today, Hopewell Junction sits astride the bike/walk Empire State Trail where it is the juncture amongst the Dutchess Rail Trail admin west to the Walkway Over the Hudson at Poughkeepsie, New York and the more recently constructed Maybrook Trailway winding through the hills to Brewster, New York to roughly meet the Putnam County Trailway and its continuations to New York City.

It was ranked #31 on Money magazine’s “Most Desirable Places to Live” for 2005.

Hopewell Junction is located close the middle of the town of East Fishkill at 41°35′N 73°48′W / 41.583°N 73.800°W / 41.583; -73.800 (41.584, -73.806), to the north of Fishkill Creek.