Mokane is a little city in southern Callaway County, Missouri, United States. The population was 185 at the 2010 census. It is ration of the Jefferson City Metropolitan Statistical Area.

The unity was first named Smith’s Landing, after Thomas Smith, who contracted there on 1818, and is said to be the second- or third-oldest town in Callaway County. The treaty later took on the make known Saint Aubert vis-а-vis the grow old a broadcast office was built there in 1849. Official Callaway County maps of 1876 feign St. Aubert, which was furthermore the pronounce of its township area. The town was still referred to as Saint Aubert considering Livingston’s “History of Northeast Missouri” went to press in 1883 or 1884.

On July 1, 1893, the Missouri, Kansas and Eastern Railway, a subsidiary of the MKT Missouri-Kansas-Texas Railroad, took possession of the rail descent that passed through the town to Saint Louis. The parentage included a station stop. Within a few years, the town customary a new name based upon the post of the railroad: Mo., Kan. & E. In 1897, Callaway County’ official map shows the town named “Mokane”. Compared to the 1876 map, it afterward moves the town one house section northward, due to the inundation of outdated Saint Aubert.

Mokane is located upon the north side of the Missouri River valley along Missouri Route 94 together with Tebbetts to the southwest and Steedman to the northeast. Fulton lies practically twelve miles to the north along Missouri Route C. The Katy Trail, a rails-to-trails hiking/biking path, runs through the town, which stands at mile 125.