Leland is a city in Washington County, Mississippi, United States. It is located within the Mississippi Delta, on the banks of Deer Creek. The population was 4,481 at the 2010 census. It was subsequently a railway town and had long been a middle of cotton culture, which is still an important commodity crop in the rural area. It was once considered the second-largest city in Washington County in 1920 due to its sudden growth of residents, businesses, and schools.

Since since the Civil War, farming has been the basis of the local economy. There are several privately-owned farms within and all but the boundaries of the town. Mississippi State University and the United States Department of Agriculture (USDA) maintain an agriculture research station at Stoneville upon Leland’s outskirts. Other agricultural companies in the Place are Lauren Farms BASF Stoneville Cotton, Bayer Crops Science, GreenPoint Ag, Azlin Seed Service, Corteva Agriscience™, Pettiet Agricultural Services, Inc., Nutrien Ag Solutions^TM, K-I Chemical U.S.A., Greenland Planting Company, Ayers-Delta Implement, Edward’s Flying Service, Essie Patterson Farm Trucking, and Southern Seed Association. Cotton, soybeans, rice and corn are the leading commodity crops along similar to catfish.

A number of national and regionally noted blues musicians are from Leland. There are five Mississippi Blues Trail markers in Leland commemorating the small town’s significant contribution to blues history. Highway 61, mentioned in numerous blues recordings, runs through the town and gives its pronounce to the community’s blues museum. Leland is the burial place of the folk performer and blues musician James “Son” Thomas, who lived for many years close the railroad tracks. Thomas is buried beneath a gravestone donated by Mt. Zion Memorial Fund, to which musician John Fogerty of Creedence Clearwater Revival was a twelve-monthly contributor.

Blues musician Johnny Winter spent part of his childhood in Leland. Winter’s grandfather and father, a former mayor of Leland, operated J.D. Winter & Sons, a cotton business. One of the Blues Trail markers in Leland is dedicated to Winter.