Hughesville is a census-designated place (CDP) in Charles County, Maryland, United States. The population was 2,197 at the 2010 census. Truman’s area was listed upon the National Register of Historic Places in 1988.

According to the United States Census Bureau, the CDP has a total area of 11.2 square miles (29.1 km), of which 11.2 square miles (28.9 km²) is land and 0.08 square miles (0.2 km), or 0.69%, is water.

Hughesville was a tobacco announce town. The former tobacco warehouses are now used for second-hand thrift stores and boutique gift and craft shops. (Historical outfit article: https://www.charlescountymd.gov/Home/ShowDocument?id=3581) A multi-lane bypass of the town by Maryland Route 5 opened in February 2007, which has alleviated previous rush-hour traffic backups at the single traffic signal; beside it are two unfamiliar side-by-side traffic roundabouts.

Because Hughesville, though small, is considered the strategic geographic center of the tri-county Southern Maryland region, it houses institutions such as the headquarters for the Southern Maryland Electric Cooperative, an animal shelter, an economic develop council, a board of realtors, and a homeless women’s shelter, which assistance the tri-county area. There is furthermore a Girl Scout camp. The town has no time-honored grid-layout streets, but consists of merely businesses along the highway and some very small outlying housing developments. It was announced in 2013 that the College of Southern Maryland is building their fourth campus in the town.