Eunice is a city in Acadia and St. Landry parishes in the U.S. state of Louisiana. The 2010 census placed the population at 10,398, a stop of 1,101, or 9.5 percent, from the 2000 tabulation of 11,499.

The St. Landry Parish ration of Eunice is portion of the Opelousas–Eunice Micropolitan Statistical Area, while the Acadia Parish ration is ration of the Crowley Micropolitan Statistical Area.

One-time lawman and pioneer home developer C.C. Duson is ascribed with founding Eunice, which was named for his second wife, Eunice Pharr Duson. He and his brother, W.W. Duson, had already founded Crowley, Louisiana in 1887, and now he looked to the north of the parish for vanguard development. Duson bought 160 acres (0.65 km) of estate from Willie Humble of Prairie Faquetaïque and mapped out a town site, laid out in lots 50-by-140 feet, 12 lots to the block. Next, he persuaded the Southern Pacific Railroad to extend a branch parentage from Crowley to his supplementary town. Then he began what he and his brother had college how to do as competently as anyone: promote estate sales. It was chartered as a village upon September 12, 1894, and incorporated as a town upon June 4, 1895.

Evangeline Parish was created similar to the alleyway of a credit in June 1908. Eunice and Ville Platte were in competition for the parish seat, and Ville Platte was agreed by voters upon April 12, 1909. After the election, Eunice confirmed it would remain in St. Landry Parish.