Simpsonville is a house rule-class city in Shelby County, Kentucky, in the United States. It is located 8 miles west of Shelbyville, Kentucky and 23 miles east of Louisville situated along U.S. 60. The population was 2,484 during the 2010 U.S. Census.

Simpsonville was first laid out in 1816 on the petition of Isaac Watkins. It normal its first read out office in 1821 and was incorporated in 1833. It was named in praise Captain John Simpson; a native Virginian who represented Shelby County in the Kentucky House of Representatives and died in the War of 1812. By 1825 it had become a stage coach town; one of the largest in the midst of Shelbyville and Louisville. The Midland trail stagecoach would either exchange out or get out of their horses and travelers could stay at the Old Stone Inn. The second oldest stone building in the county which is yet standing today.

For most of its archives Simpsonville was an agrarian community which dairy, tobacco, cattle, and hogs instinctive the primary source of allowance for most residents. This was due to its remarkably fruitful soil based upon limestone and red clay. Later on it would be the genesis for the town’s moniker ‘American Saddlebred Horse Capital of the World’.

In January 1865 at least 80 members of Company E of the 5th United States Colored Cavalry were transporting 900 head of Federal cattle from Camp Nelson to a accretion market in Louisville. They set going on camp in Simpsonville and on the day of January 25 they were attacked by Confederate guerrillas believed to be led by Henry Magruder. The guerrillas attacked from the rear killing 22 Union soldiers and injuring greater than 20 more, some of which were killed after frustrating to surrender. None of the guerrillas were documented to be injured. The Union army camped in Louisville was indifferent to the ambush, not responding for three days and leaving the citizens of Simpsonville to care for the wounded. Eventually, the wounded were transferred to an Army hospital in Jeffersonville, Indiana where a extra four more died. The citizens of Simpsonville buried the dead in two layer graves that higher became an African American cemetery, one of which is now marked next a memorial along U.S. 60. Some of the survivors future became Buffalo Soldiers.