Owensboro is a house rule-class city in and the county seat of Daviess County, Kentucky, United States. It is the fourth-largest city in the give leave to enter by population. Owensboro is located upon U.S. Route 60 and Interstate 165 virtually 107 miles (172 km) southwest of Louisville, and is the principal city of the Owensboro metropolitan area. The 2020 census had its population at 60,183. The metropolitan population was estimated at 116,506. The metropolitan area is the sixth largest in the permit as of 2018, and the seventh largest population center in the let in when including micropolitan areas.

Evidence of Native American treaty in the Place dates put up to 12,000 years. Following a series of bungled uprisings subsequently British support, however, the last Shawnee were goaded to vacate the Place before the fall of the 18th century.

The first European descendant to consent in Owensboro was frontiersman William Smeathers or Smothers in 1797, for whom the riverfront park is named. The concurrence was originally known as “Yellow Banks” from the color of the land beside the Ohio River. In 1817, Yellow Banks was formally established below the name Owensborough, named after Col. Abraham Owen. In 1893, the spelling of the make known was condensed to its current Owensboro.

Several distillers, mainly of bourbon whiskey, have been in and roughly the city of Owensboro. The major distillery still in operation is the Glenmore Distillery Company, now owned by the Sazerac Company.