Maysville is a home rule-class city in Mason County, Kentucky, United States and is the seat of Mason County. The population was 8,782 as of 2019, making it the 51st-largest city in Kentucky by population. Maysville is upon the Ohio River, 66 miles (106 km) northeast of Lexington. It is the principal city of the Maysville Micropolitan Statistical Area, which includes Mason and Lewis counties. Two bridges furious the Ohio from Maysville to Aberdeen, Ohio: the Simon Kenton Memorial Bridge built in 1931 and the William H. Harsha Bridge built in 2001.

On the edge of the outer Bluegrass Region, Maysville is historically important in Kentucky’s settlement. Frontiersmen Simon Kenton and Daniel Boone are accompanied by the city’s founders. Later, Maysville became an important port on the Ohio River for the northeastern share of the state. It exported bourbon whiskey, hemp and tobacco, the latter two produced mainly by African American slaves back the Civil War. It was past a middle of wrought iron manufacture, sending ironwork downriver to beautify the buildings of Cincinnati, Ohio, and New Orleans, Louisiana. Other small manufacturers furthermore located in advance in Maysville and manufacturing remains an important part of the futuristic economy. Under the leadership of Henry Means Walker, Maysville was house to one of the largest tobacco auction warehouses in the world for most of the 20th century.

Maysville was an important stop on the Underground Railroad, as the pardon state of Ohio was just across the river. Abolitionist author Harriet Beecher Stowe visited the Place in 1833 and watched a slave auction in front of the court house in Washington, the original chair of the county and now a historic district of Maysville. She included the scene in her influential novel Uncle Tom’s Cabin, published in 1852.

Buffalo following forded the Ohio here, beating a broad path into the interior of Kentucky in search of salt licks. For thousands of years, various cultures of native peoples inhabited the area, hunting the buffalo and additional game. In the 17th century, the powerful Iroquois Confederacy, based in present-day New York state, drove out additional tribes to sustain the Ohio Valley as a hunting ground.