Grayson is a home rule-class city in and the county chair of Carter County, Kentucky, United States, on US Route 60 and Interstate 64 in the state’s northeastern region. It is nearly 21 miles west of Ashland. Within the city limits, the population was 4,217 at the 2010 census. Along gone Carter County, the city is to the side of associated when the approachable Huntington-Ashland, WV-KY-OH Metropolitan Statistical Area and is often erroneously included in the MSA subconscious just 9 miles west of the M.S.A’s western boundary.

The city has grown in size substantially before the opening of Interstate 64 in 1975 through Carter County. Immediately afterwards, Grayson experienced several years of billboard sector growth, mainly to relief the Interstate 64 traffic. Since 1990, the city has after that seen significant buildup in the residential sector next the Interstate making for a faster vacation to and from Ashland. Beginning in 1995, AA Highway terminates in Grayson making the city a gateway to the Huntington-Ashland urban area.

After the Revolutionary War, George Washington’s aide-de-camp Col. William Grayson normal a 70,000-acre (280 km) tract of house for his encouragement during the accomplishment from the come clean of Virginia. By 1838, a small portion of this tract was set aside for the expand of a town named for him. Although Grayson had by yourself five streets and eighty lots, it was traditional by the General Assembly upon February 6, 1844, and it was incorporated on February 22, 1860.
Grayson, Kentucky was a stop on the Eastern Kentucky Railway.

Grayson is located in east-central Carter County at 38°20′5″N 82°56′33″W / 38.33472°N 82.94250°W / 38.33472; -82.94250 (38.334738, -82.942368), along the Little Sandy River, a tributary of the Ohio River.