Hypoluxo is a town in Palm Beach County, Florida, United States. The population was 2,588 at the 2010 census. As of 2018, the population recorded by the U.S. Census Bureau was 2,783. Hypoluxo Scrub Natural Area is a protected landscape.

The pedigree of the name “Hypoluxo” is disputed. One theory analyzed the make known as composed of the Greek root “hypo-“ (under, below average) and the Latin “lux” (light). Hannibel Pierce settled on Hypoluxo Island in imitation of his associates in 1873. His son, Charlie W. Pierce reported that a Seminole woman told his mom that the Seminole publicize for Lake Worth was Hypoluxo, which he thought meant ‘island’, or as he put it using his substitute command of the English language: “water whatever around, no get out”. The publicize that the Pierces wrote as “Hypoluxo” was fixed idea as “Opoloccha” in a history posted by the Town of Hypluxo. J. Clarence Simpson, citing William A. Read, states that the post is from the Creek-Seminole Hapo, meaning “mound” and Plotski, meaning “round”, thus “round mound”. The name “Hypoluxo” appears upon an 1841 War Department map.

The Place that is now the Town of Hypoluxo was first settled in 1884 by Andrew Walton Garnett, James Edward Hamilton and James William Porter. Gannett and Hamilton carried the mail with the Lake Worth area and Miami as barefoot mailmen.

Hypoluxo is located at 26°33′46″N 80°3′8″W / 26.56278°N 80.05222°W / 26.56278; -80.05222 (26.562897, –80.052339). The town is on the mainland shore of Lake Worth and does not total any of Hypoluxo Island.