Muscoy is a census-designated place (CDP) in San Bernardino County, California, United States. The population was 10,644 at the 2010 census, up from 8,919 at the 2000 census. Muscoy shares ZIP code 92407 bearing in mind the communities of Verdemont, Devore Heights, Rosena Ranch and Arrowhead Farms in northwestern San Bernardino. Residents enjoy a semi-rural setting behind large lots where they can lift horses and extra livestock, nursery plants, and fruit trees. For this reason, much of Muscoy is included in the county Additional Agriculture (AA) overlay, which specifies the types and quantities of animals that may be kept upon each parcel. A distinctive feature of Muscoy moving picture today is motor vehicles and equestrians sharing the roadways.

Muscoy was developed in the mid-1890s as a community designed to accommodate relations agricultural
enterprises. Roads and water assistance were developed to advance one to ten acre parcels. Vineyards, orchards and various arena crops were planted and cultivated. After World War II, population bump accelerated and the Place began a transition from agricultural use to a more suburban residential character. During the 1950s and 1960s, the San Bernardino area became a popular End during road trips. This resulted in more shops establishment up to help the needs of travelers, and more people establishing unshakable residences in this area the Muscoy area. In 1989, a gasoline pipeline explosion caused two deaths.

Muscoy is located at 34°9′22″N 117°20′48″W / 34.15611°N 117.34667°W / 34.15611; -117.34667 (34.156009, -117.346552). Elevation ranges from 1240′ in the south to 1600′ in the north.

According to the United States Census Bureau, the CDP has a total area of 3.1 square miles (8.0 km), 99.87% of it is land and 0.13% is water.