La Crescenta-Montrose (pronunciation) is an unincorporated Place in Los Angeles County, California, United States. The community is bordered by Glendale to the south and west, La Cañada Flintridge to the east, and Angeles National Forest to the north. According to the United States Census Bureau, the La Crescenta-Montrose Census-Designated Place (CDP) measures nearly 3.4 square miles (8.8 km²), and the population was 19,997 at the 2020 census, up from 19,653 in 2010 and 18,532 in 2000.

La Crescenta-Montrose encompasses those parts of the Crescenta Valley, northwestern San Rafael Hills, and northeastern Verdugo Mountains not within the cities of Glendale or La Cañada Flintridge. For statistical purposes, the United States Census Bureau has defined La Crescenta-Montrose as a CDP.

La Crescenta-Montrose is bordered upon the north by the San Gabriel Mountains and Angeles National Forest, on the east by La Cañada Flintridge, on the south by the Verdugo Mountains and central Glendale, and the northwest by the Sunland-Tujunga community of Los Angeles. The Foothill Freeway (I-210) runs through the southern allocation of the area.

The 2010 United States Census reported that La Crescenta-Montrose had a population of 19,653. The population density was 5,717.8 inhabitants per square mile (2,207.7/km²). The racial makeup of La Crescenta-Montrose was 12,807 (65.2%) White (57.9% Non-Hispanic White), 142 (0.7%) African American, 70 (0.4%) Native American, 5,375 (27.3%) Asian, 12 (0.1%) Pacific Islander, 533 (2.7%) from new races, and 714 (3.6%) from two or more races. Hispanic or Latino of any race were 2,232 persons (11.4%).