Hopland (formerly Sanel) is a census-designated place in Mendocino County, California, United States. It is located upon the west bank of the Russian River 13 miles (21 km) south-southeast of Ukiah, in the Sanel Valley, at an height of 502 feet (153 m). The population was 661 at the 2020 census, down from 756 at the 2010 census.

Hopland is located at the Begin of the North Coast or Redwood Coast region of Northern California. It is 100 miles (161 km) north of San Francisco along U.S. Route 101 and a 30-minute drive (17 miles [27 km] east along State Route 175) to California’s largest natural lake, Clear Lake. Hopland is a rustic cultivation community situated in the midst of oak-covered coastal foothills. Summer temperatures can exceed 100 °F (38 °C).

Historic buildings in town insert the obsolescent Hopland High School (c. 1923–1965), currently the competently known and beloved Bluebird Cafe, the Brutocao Cellars tasting room; as well as the Thatcher Hotel, built in the late 1800s and recently reopened after undergoing a supreme renovation. Other establishments in Hopland include Cafe Poppy, The Golden Pig, Hopland Tap House, Brutocao Cellars, Saracina Winery, Campovida Winery and Fetzer Vineyards, a major producer of both red and white wines in North America, including Zinfandel, Chardonnay and Merlot.

Approximately 5 mi (8 km) east of Hopland is the University of California’s Hopland Research and Extension Center (formerly called the “Hopland Field Station”), a 5,300-acre (21.4 km) research and education skill that UC has operated past 1951.