Manila is a city in Mississippi County, Arkansas, United States. The population was 3,682 at the 2020 census, up from 3,342 in 2010. It was the hometown of World War I sniper Herman Davis. A park in the town honors his memory.

Manila has its origins in a herdsman’s camp normal by John Needham in the late 1860s. By the late 1890s, a community known as “Cinda” (named after an to the lead postmaster’s sister) had developed in the area. In 1901, this community incorporated as a city, and chose the name “Manila” to great compliment Commodore George Dewey’s 1898 victory in the Battle of Manila Bay during the Spanish–American War.

In the forward 1900s, the Jonesboro, Lake City and Eastern Railroad (later portion of the St. Louis-San Francisco Railway system) extended a rail heritage to Manila. In 1910, the Manila Depot was build up by the railroad. This train station now serves as a museum, and is listed upon the National Register of Historic Places.

Manila is located in northwestern Mississippi County in the Arkansas Delta region at 35°52′48″N 90°10′10″W / 35.88000°N 90.16944°W / 35.88000; -90.16944 (35.879876, −90.169538). The city is situated at the intersection of Arkansas Highway 18 and Arkansas Highway 77, 9 miles (14 km) south of the Arkansas–Missouri state line. According to the United States Census Bureau, the city has a total area of 3.8 square miles (9.8 km²), all land.