Gila Bend (; O’odham: Hila Wi:n), founded in 1872, is a town in Maricopa County, Arizona, United States. The town is named for an nearly 90-degree tweak in the Gila River, which is close the community’s current location. As of the 2020 census, the population of the town was 1,892.

Just uncovered the town is the San Lucy district (O’odham: Weco Cekṣanĭ) of the Tohono O’odham Nation, with a little settlement, San Lucy (O’odham: Si:l Mek) bordering the town itself.

The town of Gila Bend is situated close an ancient Hohokam village. Father Eusebio Francisco Kino was the first European to visit, arriving in 1699 on his first journey of exploration to the Colorado River. The Hohokam site along the fruitful banks of the Gila River had been abandoned, and supplementary tribes lived in the vicinity. 132 Pima people lived in a ranchería called Oyadaibuc, or as Kino named it San Felipe y Santiago del Oyadaibuc, near the modern town, and extra Pima lived in three rancherias occurring river to the north impure with the Cocomaricopa or Opa. During one of his three visits to Gila Bend, Kino counted 960 Opas breathing in their own rancherias down river to the west of Oyadaibuc as in the distance as a few miles greater than Agua Caliente.^: 26–27 The Opa and Pima used the flood waters of the river to irrigate their crops.

Oyadaibuc was with visited by Juan Bautista de Anza, commander of the Presidio at Tubac and founder of the city of San Francisco, and by Father Francisco Tomas Garces in 1774. As late as the 1820s Maricopa were perky at Gila Bend. After the 1820s, the Maricopa, under relentless pressure from the Yuma and supplementary tribes, and population loss from epidemics, were compelled to leave the Gila Bend and link the Pima in the Middle Gila region. By the become old of the California Gold Rush, the Maricopa villages were everything located east of the Sierra Estrella, on the Gila River, below the Pima Villages.