Rogersville is a town in Lauderdale County, Alabama, United States. As of the 2018 census, the population of the town is 1,231, up from 1,199 in 2000.

The town became an incorporated municipality on February 2, 1858. Originally known as “Rodgersville”, it took its name from Andrew and Patience Rodgers of South Carolina who moved into the Place and purchased 79.8 acres (323,000 m²) at a public home sale in Huntsville upon May 3, 1818. Their estate eventually became what is now the downtown event district. When the Rogersville Post Office was established upon October 4, 1825, with Thomas Cunningham as the postmaster, the ‘d’ was dropped from the town’s herald and it has been known as Rogersville ever since.

The town became a popular trading middle due in share to its location close the intersection of three forward thoroughfares, U.S. 72, Snake Road and Lamb’s Ferry Road. U.S. 72, which now connects Chattanooga and Memphis, Tennessee, was in the same way as part of an Indian trail from Ditto’s Landing on the Tennessee River south of Huntsville and was used to bypass the Muscle Shoals river barrier. Snake Road leads out of Rogersville into adjacent to Limestone County and provided path from Florence to Athens by way of a shallow ford across Elk River. Lamb’s Ferry Road was named for John Lamb who moved from Indian Creek in Giles County, Tennessee in 1816 to uphold a ferry across the Tennessee River south of what would later become Rogersville. Lamb’s Ferry became an important river port where boats from Knoxville and extra points on the upper Tennessee River would unload supplies that were taken beyond land to areas on the order of Pulaski, TN.

Rogersville is located at 34°49′24″N 87°17′8″W / 34.82333°N 87.28556°W / 34.82333; -87.28556 (34.823444, -87.285693). According to the U.S. Census Bureau, the town has a total Place of 3.1 square miles (8.0 km²), all land.