Wayne is a town in, and the county chair of, Wayne County, West Virginia, United States. The population was 1,441 at the 2020 census. Wayne is a allocation of the Huntington-Ashland, WV-KY-OH, Metropolitan Statistical Area. As of 2015, the MSA had a population of 361,580.

Wayne was normal in 1842, by the thesame act of the Virginia General Assembly that created Wayne County. The county was named for General “Mad Anthony” Wayne. The town was initially known by the name “Trout’s Hill,” after Abraham Trout, who donated the land upon which the county’s courthouse was built. The Wayne Courthouse Post Office was expected in 1842 also. The town was known simultaneously as Trout’s Hill and Wayne Courthouse for many years. The town was incorporated in 1860 and 1882 as Fairview, but was yet commonly known as Wayne Courthouse. The population in 1882 was 157. In 1890, the Norfolk & Western Railroad was build up up Twelve Pole Creek. The railroad placed the name “Wayne” on its schedule and the post caught on. The say was officially misused to Wayne in 1911.

Settlers arrived near the town of Wayne in the early 1800s. Abraham Trout began operational a mill where the town now stands in 1828 at a waterfall on Twelve Pole Creek. Later on, he built a mill dam.

By the 1830s, the population in western Cabell County was growing, and it became essential to form a supplementary county in the area. Initially, a outfit of men from the Big Sandy River attempted to gain a county created in 1840 like the county chair at the forks of the immense Sandy River where gift Fort Gay is now located but it failed. A year later, men from Twelve Pole began practicing toward a supplementary county as soon as the county chair near the forks of Twelve Pole Creek. They were successful, and the new county was established upon January 18, 1842 and named after General Anthony Wayne.