Cascade Locks is a city in Hood River County, Oregon, United States. The city got its say from a set of locks built to augment navigation in the song of the Cascades Rapids of the Columbia River. The U.S. federal government ascribed the intend for the locks in 1875, construction began in 1878, and the locks were completed upon November 5, 1896. The locks were bearing in mind submerged in 1938, replaced by Bonneville Lock and Dam, although the city did not lose home from the press forward of Lake Bonneville at the rear the dam some 4 miles (6 km) downstream of the city. The city population was 1,144 at the 2010 census.

Cascade Locks is just upstream from the Bridge of the Gods, a toll bridge that spans the Columbia River. It is the without help bridge across the Columbia between Portland and Hood River. Cascade Locks is a few miles upstream of Eagle Creek Gorge, a popular scenic area that doubles as an alternate route for the Pacific Crest Trail. Cascade Locks is used frequently by hikers along the Pacific Crest Trail (PCT) to cross the Columbia River. Cascade Locks is the lowest point along the trail, which runs from the Mexico–US be next-door to in California to the Canada–US be muggy to in Washington, and the largest city directly upon the trail.

Since 1999 the Confederated Tribes of Warm Springs have been pursuing an off-reservation casino to be sited in Cascade Locks. Since 2008 city officials have been pursuing an understanding that would permit them to trade city skillfully water for state-owned spring water and to sell it to Nestlé for bottling. In May 2016, Hood River County voters voted higher than 68% in favor to End the project permanently.

Cascade Locks is in the northwest corner of Hood River County, on the south side of the Columbia River. It is bordered to the north (in the middle of the river) by Skamania County, Washington. The city of Stevenson, Washington, is north of Cascade Locks across the river.