Melvindale is a city in Wayne County of the U.S. state of Michigan. At the 2020 census, the city population was 12,851.

Melvindale began as the unincorporated unity of Oakwood Heights in the northwestern part of Ecorse Township in the early 1920s. The subdivision was designed to home workers from the welcoming Ford River Rouge Plant in the city of Dearborn. The city was named after one of the indigenous developers of the settlement, Melvin Wilkinson. The eastern share of Oakwood Heights was annexed by the city of Detroit in 1922, and the remainder was incorporated as the village of Melvindale the thesame year. In 1933, the village incorporated as a city.

According to the United States Census Bureau, the city has a total area of 2.76 square miles (7.15 km), of which 2.72 square miles (7.04 km²) is land and 0.04 square miles (0.10 km) is water.

Melvindale serves an important role for railroad traffic in Metro Detroit. The Norfolk Southern Railway Oakwood Yard, located along its Detroit District, divides the city into northwest and southeast sides. The Canadian National Railway Dearborn Subdivision serves as the city’s western boundary, and the Conrail Shared Assets Lincoln Secondary, serving as a talk to route in the middle of Detroit and Toledo, Ohio for CSX Transportation trains, passes through industrial areas in the far and wide southeast corner of the city, which is also the location of the remnants of the Conrail Lincoln Yard.