Argentine is an unincorporated community and census-designated place (CDP) in Argentine Township, Genesee County, in the U.S. state of Michigan. The population was 2,525 as of the 2010 census, up from 2,285 at the 2000 census. It was first contracted in 1836.

The Place included in the CDP is the southeast corner of Argentine Township. The city of Linden is to the east, and the Linden ZIP code 48451 next serves Argentine.

The first settlers, Jame H. Murray and William Lobdell, arrived in 1836. A name office, “Booton”, was opened upon November 1, 1837, with Murray as the first postmaster. The proclaim office was renamed “Argentine” on March 30, 1942, due to a similarly named declare office. The community was platted by Dr. Isaac Wixom in 1844.

Argentine is in southern Genesee County, in the southeast corner of Argentine Township. The CDP extends east to the border of Fenton Charter Township, and the southern edge of the CDP follows the Genesee–Livingston County line. The CDP includes the Genesee County allocation of Lobdell Lake and its surroundings, and extends west to total Murray Lake and north to the Shiawassee River. The center of the community is at the intersection of Silver Lake Road and South Seymour Road, at the northwest halt of Lobdell Lake. Silver Lake Road leads northeast 4 miles (6 km) to Linden and northwest 6 miles (10 km) to Byron, while South Seymour Road leads south into Livingston County, where it becomes Argentine Road.