East Lake-Orient Park is an unincorporated census-designated place in Hillsborough County, Florida, United States. The population was 22,753 at the 2010 census, up from 5,703 at the 2000 census in imitation of an move forward of its borders. The Place is the home of the Florida State Fairgrounds, which hosts the Florida State Fair in mid-February of each year. It was previously house to East Lake Square Mall. The ZIP code for East Lake-Orient Park is 33610 (East Lake) and 33619 (Orient Park).

East Lake-Orient Park is located in north-central Hillsborough County at 27°58′42″N 82°22′26″W / 27.97833°N 82.37389°W / 27.97833; -82.37389 (27.978399, -82.374017). The CDP includes the communities of East Lake, Orient Park, and Del Rio. It is bordered by the city of Tampa to the south and west, Temple Terrace to the north, Thonotosassa and Mango to the east, and Brandon to the southeast. U.S. Route 301 and Interstate 4 run through the community, crossing near the middle of the CDP. US 301 leads northeast 21 miles (34 km) to Zephyrhills and south 9 miles (14 km) to Riverview, while I-4 leads east 27 miles (43 km) to Lakeland and west 8 miles (13 km) to downtown Tampa. Interstate 75 forms the eastern edge of the East Lake-Orient Park CDP, leading north 93 miles (150 km) to Ocala and south 42 miles (68 km) to Bradenton.

According to the United States Census Bureau, the CDP has a total area of 17.4 square miles (45.0 km), of which 16.3 square miles (42.3 km²) are estate and 1.0 square mile (2.7 km), or 6.06%, are water. The Tampa Bypass Canal crosses the CDP from north to south.

As of the census of 2010, there were 22,753 people, residing in the census area. The population density was 1,302.0 inhabitants per square mile (502.7/km²). The racial makeup of the census Place was 42.8% White, 47.3% Black or African American, 0.4% Native American, 2.1% Asian, 3.7% from supplementary races, and 3.6% from two or more races. Hispanic or Latino of any race were 16.9% of the population.