Oxford is a city in Calhoun, Talladega, and Cleburne counties in the State of Alabama. The population was 22,069 at the 2020 census,. Oxford is one of two principal cities of and included in the Anniston-Oxford Metropolitan Statistical Area, and it is the largest city in Calhoun County by population.

Founded in the ahead of time 1850s, Oxford was the first city in Calhoun County to be incorporated, in 1852. The name “Oxford” was due to the presence of a narrow crossing of Chocolocco Creek that allowed farmers to ford cattle from one side of the creek to the other. Since 1970, Oxford has annexed large amounts of home to the south and west, including the communities of Coldwater and Bynum. In 1970, it was anything in Calhoun County, but today it includes areas in Talladega County and Cleburne County.

A smaller municipality, Hobson City, was in the same way as a part of Oxford. The area, then known as the Mooree Quarter, is one square mile, and is located north and west of Oxford, and south and west of Anniston. The new town became incorporated on August 16, 1899 as Hobson City, taking the make known of a naval hero of the Spanish–American War. Another result was the instigation of unaided the second town in the United States (after Eatonville, Florida) with 100% black government, and an on 100% black population (at least at first).

According to the U.S. Census Bureau, the city has a total area of 32.2 square miles (83.3 km), of which 31.72 square miles (82.15 km²) is home and 0.35 square miles (0.9 km), or 1.07%, is water.